The Top 10 Clinical Research Companies in the USA

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  • Dec 02, 2022
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The Top 10 Clinical Research Companies In The USA

To bring effective medicines and Innovations in healthcare industry, a Clinical Research Organization or Contract Research Organization (CRO) are a must for the Biotech, Medtech, and pharma industries. A CRO offers comprehensive support to their efforts to test, examine, refine and market the latest medicines and devices that help in improving Healthcare Industry.

In 2022, the global clinical research market stands at $63.6 billion, and by 2027, it is expected to reach around an exciting amount of 115.1 billion with a CAGR of 11.0% from 2022 to 2027.

This growth is powered by an increase in R&D activities and expenditures and a significant rise in clinical trials owing to the need for innovations in healthcare. For that reason, it is also essential to be aware of the most prominent global research organizations that offer vital support with their specialized clinical trial solutions. This post will walk you through the ten big Clinical Research Companies In USA. So, let’s begin:


  • Founded: 1982
  • Headquarters: Durham, North Carolina
  • Annual Revenue: $13.87B
  • Employee Size: 88,000

IQVIA is one of the largest Clinical Research companies in the world that works profusely to enhance healthcare by integrating the study of human science with discoveries in technology and data science to improve understanding of human health and provide better and quicker care.

It helps pharma companies, along with other medical organizations, to innovate and maximize positive outcomes. In addition to clinical research and development, IQVIA has also developed analytics and technology solutions to aid the medical sector in commercializing products and enhancing customer engagement.

Some clinical trial solutions given by IQVIA are as follows:

  • Site identification & Selection
  • Help with protocol design
  • Design of clinical trial phase -1
  • Investigation and improvements of the clinical trial in phases 2 and 3
  • Accessibility to global laboratories

2. Pharmaceutical Product Development (PPD)

Pharmaceutical Product Development
  • Founded: 1985
  • Headquarters: Wilmington, North Carolina
  • Annual Revenue: $65.0M
  • Employee Size: 24,000

PPD, also known as Pharmaceutical Product Development, is an extensive research organization headquartered in the United States but has a widespread global presence.

The company directs its attention to three prime areas: pharma development, lifecycle management services, and laboratory. Besides, it has clients and partners covering various sectors, including pharmaceutical companies, biotech firms, medical device manufacturers, and government or academic organizations. 

Some clinical trials offered by PPD include:

  • Early Development
  • Consulting and Product Development
  • PPD Biotech
  • The site and patient-centered Solutions
  • Clinical Development

3. Parexel

  • Founded: 1982
  • Headquarters: Waltham, Massachusetts
  • Annual Revenue: $3B
  • Employee Size: 18,000

Parexel is another important name in the list of Clinical Research Companies In USA that specializes on behalf of its pharmaceutical partners in carrying out clinical studies to boost and make certain that the medicine approval process takes place smoothly. It has a wide range of offerings that spreads across every type of clinical trial service to help sponsors work on creating successful trials.

Some of the clinical trial solutions which Paraxel offers:

  • Management of clinical data
  • Medical writing
  • Biostatics
  • Regulatory affairs consulting
  • Design and development of clinical trials at all phases
  • Clinical supply chain management

With pride, the company operates in over 50 countries and owns over 95% of the top 200 selling biopharmaceuticals in today’s market.

4. PRA Health Services

PRA Health Services
  • Founded: 1976
  • Headquarters: Raleigh, North Carolina
  • Annual Revenue: $64.3M
  • Employee Size:16,400

PRA Health Sciences is a contract research organization that provides coverage in more than 90 countries worldwide. It principally centers on contributing therapeutic and operational expertise through integrated applications and supplying local expertise in particular areas. Besides, it works in the early and end stages of clinical trial procedures and the domains of strategy, consultancy, technology, and bio-analytics.

Moreover, it works hard to speed up medicine development operations to introduce better and more effective medicine sooner in the market.

Let’s take a peek at the PRA Health Sciences clinical trial solutions:

  • Onsite support services
  • Personalized solutions for Biotech
  • Clinical Diagnostics
  • Site Commercial Solutions
  • Protocol Consultation and Study Design
  • PRA’s Laboratories for Medicine Development

5. Syneos Heath

Syneos Health
  • Founded: 1999
  • Headquarters: Morrisville, North Carolina
  • Annual Revenue: $5,213M
  • Employee Size: 28,000

With the merger of inVentiv Health and INC Research, Syneos Health was created that combines every discipline involved in bringing new therapies or products to market, from clinical research to consulting and commercialization.

Though it provides clinical development services spanning all stages, it primarily owns a specialization in helping healthcare organizations with the late stages of clinical trials. Moreover, its commercial solutions cover communication, consulting, and medication adherence.

The clinical trial solutions it offers include:

  • Early phase
  • Late phase
  • Decentralized clinical trial solutions
  • Clinical data management
  • Pharmaceutical
  • Medical Device Diagnostics

6. LabCorp

  • Founded: 1978
  • Headquarters: Burlington, North Carolina
  • Annual Revenue: $16.1B
  • Employee Size: 70,000

Laboratory Corporation of America, or LabCorp, focuses on offering extensive clinical laboratory solutions and end-to-end medication and diagnostic development and commercialization.

The company develops special testing operations such as HIV genotyping, oncology testing, phenotyping, clinical trials, and diagnostic genetics. Moreover, its services are spread through care organizations, hospitals, government agencies, pharmaceutical companies, and physicians.

Some clinical trial solutions provided by LabCorp are:

  • Preclinical Services
  • Post-Marketing Solutions
  • Medical Devices
  • Clinical Trial Laboratory Services
  • Clinical Trials
  • Data & Technology

7. Charles River Lab

Charles River Lab
  • Founded: 1947
  • Headquarters: Wilmington, Massachusetts
  • Annual Revenue: $690.4M
  • Employee Size: 20,000

Charles River laboratories proudly span its capabilities throughout the medical R&D process from basic research to pre-clinical stage testing, manufacturing and commercialization within two significant services: Good Laboratory Practice (GLP) and non-GLP. It offers precise support to help its partners advance their research and efforts to introduce effective medicines in the market.

The company further serves biotechnology and pharmaceutical companies, hospitals, government agencies, and academic institutions.

Some of the clinical development solutions it offers include:

  • Bioanalysis
  • Clinical Kitting services
  • Data management
  • Biomarkers
  • Quality control
  • Stability testing

8. Fisher Clinical Services

Fisher Clinical Services
  • Founded: 1989
  • Headquarters: Center Valley, Philadelphia
  • Annual Revenue: $17B
  • Employee Size: 50,000

Fisher Clinical Services is a part of Thermo Fisher Scientific that has been for over 20 years in the business of supply chain management. It focuses exclusively on working with distribution and packaging requirements of clinical trials happening around the globe.

The company is committed to providing high-value products which adhere to the standard of pharmaceutical companies and is reliable, sustainable and perform well.

Some of the clinical trial solutions offered by Fisher Clinical Services are:

  • Cell & Gene Therapy
  • Clinical Label Services
  • Clinical Supply Optimization services
  • Direct to patient
  • Biologistics management

9. Medpace Holdings

Medpace Holdings
  • Founded: 1992
  • Headquarters: Cincinnati, Ohio
  • Revenue: $1B
  • Employee Size: 1,001-5,000

Medpace offers support services for phases one to five of clinical trials for biotechnology, pharmaceutical companies, and medical device industries. It is a scientifically-driven organization that offers full service and helps industries make key differences with their contributions to the healthcare sector.

Some of the clinical research solutions that you receive from Medpace are:

  • Medical Writing
  • Quality Assurance
  • Clinical Monitoring
  • Clinical Trial Management
  • Risk-based Monitoring
  • Regulatory Affairs
  • Biostatistics and Data sciences

10. Advanced Clinical

Advanced Clinical
  • Founded: 1994
  • Headquartered: Deerfield, Illinois
  • Annual Revenue: $106M
  • Employee Size: 501-1,000

A mid-size and full-service Clinical Research organization that helps sponsors run clinical trials and offers various solutions across therapeutic fields. It allows clients to secure better outcomes through candid discussions, conversations, foresight, and innovative solutions.

The company works hard to improve every life touched by clinical research. As such, some clinical solutions provided by Advanced Clinical are:

  • Project management
  • Clinical monitoring
  • eTMF and document management
  • Medical writing
  • Quality & Validation
  • Biometrics

The Bottom Line

There you have it – the best Clinical Research Companies In USA to get support from while working on new medicine or medical devices.

CROs play a critical role in the pharmaceutical, biotech, and medical device industries to manage and lead their clinical trials now more than ever due to rapidly rising prices, regulations, and tighter deadlines. Also pharmaceutical companies approaching Clinical Research Organizations for their R&D activities to stay competitive, flexible, and profitable against all odds.

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Sam Wilson, Consultant